Introduction Current oncology radiopharmaceutical therapies rely on a single biomarker target to deliver cytotoxic radiation to tumors. However, tumor heterogeneity and receptor variability often limit efficacy of these radiotherapeutics. Dual-biomarker
Introduction Mayo Clinic dosed the first patient last week with Ac-225-DOTATATE radiotherapeutic (RYZ101), an alpha-emitter, by RayzeBio (a BMS company), for metastatic, estrogen receptor–positive (ER⁺), human epidermal growth factor receptor
Actinium-225 (Ac-225), 136Ac89, is an important radioisotope in nuclear medicine with applications in the targeted alpha therapy (TAT) in oncology. Ac-225 contains 89 protons and 136 Neutrons, corresponding to atomic mass
This blog discusses radiohybrids, theranostics and theranostic pairs. Radiohybrids is a modality in nuclear medicine that allows diagnostic imaging or therapeutic treatment with the same molecular entity depending on the radioelement in the molecule.
Introduction Current oncology radiopharmaceutical therapies rely on a single biomarker target to deliver cytotoxic radiation to tumors. However, tumor heterogeneity and receptor variability often limit efficacy of these radiotherapeutics. Dual-biomarker
Introduction Mayo Clinic dosed the first patient last week with Ac-225-DOTATATE radiotherapeutic (RYZ101), an alpha-emitter, by RayzeBio (a BMS company), for metastatic, estrogen receptor–positive (ER⁺), human epidermal growth factor receptor
Actinium-225 (Ac-225), 136Ac89, is an important radioisotope in nuclear medicine with applications in the targeted alpha therapy (TAT) in oncology. Ac-225 contains 89 protons and 136 Neutrons, corresponding to atomic mass
This blog discusses radiohybrids, theranostics and theranostic pairs. Radiohybrids is a modality in nuclear medicine that allows diagnostic imaging or therapeutic treatment with the same molecular entity depending on the radioelement in the molecule.
“Supply Chain Logistics For A PET Radiotracer Manufacture”
Supply chain for an 18F radioisotope based PET radiotracer manufacture is discussed in detail along with brief manufacturing descriptions provided for context. A critical report for supply chain, manufacturing, business and investing personnel to familiarize with the basics of supply chain for this category of high application, commercially critical PET diagnostic imaging agents.
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